10 Reasons Why CBD is Not a Fad
1. ANTI-INFLAMMATORY EFFECT
Its anti-inflammatory effects are proven, Bruni et al. and her research team have compiled an excellent recent review of the large volume of data that is now present regarding cannabidiol, its anti-inflammatory effect, and mechanism of action. ¹ We have seen excellent results, attributed, in part, to its anti-inflammatory effect in our pain management clinic over the last year.
2. CBD AND PHYSIOLOGY INHERENT IN OUR BODY
Cannabidiol (CBD) affects the Endocannabidiol System; this is a biologic system that is endogenous to all our bodies and has profound and wide-ranging effects on our nervous system. This system, discovered in the 1980s has given us a window to the wide-ranging effects of the CB1 and CG2 receptors and the effects of cannabidiol as it modulates this system. Simply put, this is a chemical compound and its effect on multiple receptors in an endogenous biologic system in every one of our bodies — pure Science, not a fad.
3. LACK OF ABUSE
It does not have dependency or addiction issues. All too often, many of the medicines that we, as physicians, prescribe, the behavioral consequences are profound and unfortunately, unpalatable for patients and healthcare providers. CBD, recently studied and evaluated by the World Health Organization, has shown very reassuring lack of abuse profile:
“As noted above, CBD does not produce the effects that are typically seen with cannabinoids such as THC. It also failed to produce significant effects in a human study of abuse potential.”²
4. LOW SIDE EFFECT PROFILE
Separate from its reassuring behavioral profile (in terms of lack of abuse potential), CBD use has demonstrated a very favorable low side effect profile. As we know form many of the medications that we prescribe for pain, side effects can include constipation (opioids), renal failure and gastrointestinal bleeding (NSAIDs), slurred speech and cognitive delay (neuropathic agents)
3. Ruth Gallily1, et al., Overcoming the Bell‐Shaped Dose‐Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology & Pharmacy, 2015, 6, 75‐85
5.NATURAL PART OF THE HEMP PLANT
CBD is natural. There have been efforts to create synthetic CBD products, including isolating only certain subparts CBD for use for certain conditions. The success of using isolate forms of CBD was refuted in a 2015 study from the Lautenberg Center for General Tumor Immunology in Jerusalem. ³ In this study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief compared to isolate forms of CBD.
The pharmaceutical industry has supported the development of synthetic cannabinoids for use in healthcare. This limits the ability to exploit the desirable entourage effect that comes from all the parts of the cannabis plant, which leads to more promising effects with CBD use.
6. PROMISING BENEFIT IN MANY HEALTHCARE ARENAS
CBD has emerging benefits outside of pain and inflammation (neurological conditions, endocrine conditions, etc.). There are active research and clinical benefits and even FDA approval regarding CBD and many different clinical aspects. CBD has long been shown to benefit refractory epilepsy populations and been recently approved by the FDA in a specific pediatric epilepsy population. In the neurodegenerative field, Dr. Peres et al. recently authored an article on CBD and promising results with movement disorders In addition to a litany of articles in the neurodegenerative field, the endocrinology field has been looking at CBD as a means for helping blood glucose regulation with Dr. Jandoon et al. recently authoring an article in Diabetes Care Journal. ⁴ These are a few examples of CBD and its benefits, just starting to be explored in a variety of different medical fields.
7. TECHNOLOGY HELPING EASE OF EXTRACTION
CBD can be successfully extracted from the Hemp plant, virtually eliminating the concern for cognitive effects found when using THC found in higher levels in the marijuana plant. We see that the vast majority of our patients seek CBD, in part, due to its lack of cognitive issues (aka the high associated with THC). The hemp industry has vastly increased the safety and efficiency of CBD extraction. We advise all people interested in CBD to make sure their particular CBD company is transparent with third-party testing (showing THC percentages less than 0.3%).
8. THE ENDOCANNABINOID SYSTEM IS SCIENCE
Although not well or poorly understood for many years until more recently, this system is important enough that it is now being taught in medical schools, researched at the most prestigious of academic centers, and one of the most exciting topics of medical research and development seen in decades.
9. THE PATIENTS ARE REAL
We are practicing physicians who have treated thousands of patients. Over the last decade and a half, we have seen many different medications come and go. Some provide excellent relief, and some cause terrible side effects. As physicians, we feel that a broad armamentarium of treatments is important when dealing with complex patients and complex medical issues. We have embraced CBD as a treatment for our patients as we have seen tremendous benefits and minimal side effects, often limiting the need for many other traditional medications that have a far worse side effect profile. In summation, our patients have been using CBD, and we are seeing them getting real results.
10. THE FUTURE IS BRIGHT FOR CBD
Many different aspects of the medical field are taking notice in regards to the endocannabinoid system, CBD specifically, and potential benefit. Recently a very interesting scholarly article was published in regards to CBD in the substance abuse field.⁵ We have seen from other healthcare providers and patients alike a push for a more natural approach to their medical maladies. We feel only the best outcomes from healthcare come when all options are available, and we feel that CBD will have a place in the healthcare spectrum in a variety of medical specialties.
1. Molecules. 2018 Oct; 23(10): 2478
2. Martin-Santos, R., et al., Acute effects of a single, oral dose of d9- tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers. Curr Pharm Des, 2012. 18 (32): p. 4966-79.
3. Front Pharmacol. 2018; 9: 482
4. Diabetes Care 2016 Oct; 39(10): 1777-1786
5. Front Psychiatry. 2019; 10: 63
Ask Us About CBD!
There is a lot to learn about this amazing molecule and how it can improve your health!
Feel free to ask us all your CBD-related questions on social media and we will be sure to answer.